Cold Chain Protocol – Vaccines and Biologics

Table of Contents Cold Chain Protocol

1.  Introduction and the Importance of Cold Chain
     1.1    What is Cold Chain?

2.  Cold Chain Responsibilities
      2.1    Identification of Responsibility
      2.2    Assigning Duties and Tasks to Personnel
      2.3    Contact Lists

3.   Management and Accountability
       3.1    Accountability of Vaccines and Biologics
       3.2    Inventory Management
       3.3    Expired or Unusable Products

4.   Storage Practices for Vaccines and Biologics
       4.1    Ordering Vaccines and Biologics from Manitoba Health, Seniors and Active Living
       4.2    Placement of Vaccines and Biologics in the Refrigerator

5.   Cold Chain Management Equipment
       5.1    Refrigerators for Vaccines and Biologics
       5.2    Types of Refrigerators
       5.3    Modifications to Improve Domestic Fridge Temperature Stability
       5.4    Refrigerator Maintenance
       5.5    Temperature Recording Devices
       5.6    Thermometer Placement

6.   Temperature Monitoring
       6.1    Temperature Monitoring by Assigned Personnel

7.   Packing, Storage and Handling for Off-Site Immunization Clinics
      7.1    Basic Principles
      7.2    Equipment for Transport to Off-Site Clinics
      7.3    Packing for Transport
      7.4    Maintaining Cold Chain at an Off-Site Clinic

8.   Managing Cold Chain Problems
      8.1    What to do When the Temperature is Below +2°C or Above +8°C
      8.2    Inventory Management of Cold Chain Failures
      8.3    Refrigerator Malfunctions

Resource Forms


Communicable Disease Control (CDC)
Public Health
Manitoba Health, Seniors and Active Living

4th Floor - 300 Carlton St.
Winnipeg MB  R3B 3M9  CANADA
Phone: 204-788-6737
Fax: 204-948-2040